The future of cardiac pacing.
The Need
Over 1 million pacemakers are implanted worldwide each year 1. Leadless pacemakers, such as the Medtronic Micra AV, are fully implantable and, therefore, increase patient comfort; however, the decreased size also causes a decreased lifespan, increasing the frequency of replacement surgeries to every 8-13 years on average2.
Surgeries involve risk of infection or cardiac perforation3. Increasing the battery life of the pacemaker would allow for increased patient comfort by decreasing the frequency of pacemaker insertion surgeries and office visits and decreasing patient risks.
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Traditional Pacemaker CPR Test © |
Micra AV Pacemaker Medtronic © |
Product
In order to combat the short lifespan of the Medtronic Micra AV pacemaker, our cardiac energy harvesting device converts mechanical energy created by the heart into electrical energy to recharge the pacemaker.
Side view of the device.
Testing apparatus.
The Design
Our design includes a sleeve to encase the pacemaker and electronic circuit, two magnets whose attraction allows them to move synchronously, a copper coil around the sleeve and between the magnets, and a stent to move the magnets. The movement of the magnets induce a current in the coil to recharge the pacemaker.
Testing apparatus for proof of concept.
Competitors
| Device | Requires 1 surgery for up to 26 years | Leadless Pacing System | Simple Surgery (catheter) | Fully Implantable |
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| Traditional Pacemaker |
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| Micra AV Pacemaker |
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| Micra AV Pacemaker + Our Device |
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Market
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Micra AV belongs to Medtronic’s division with highest net sales4. Medtronic © |
Market Summary by Mordor Intelligence © |
With the global and U.S. pacemaker market growing every year, our device has increasing market opportunities. The leadless pacemaker market is estimated to grow at a CAGR of 10.0%5 and have a global market value of over 50 million USD in the next few years6. We hope to market our device along with these pacemakers by partnering with Medtronic, Abbot Laboratories, and EBR Systems Inc.7.
By marketing our product to physicians and hospitals we will have a continuous stream of new customers. Our device coupled with a leadless pacemaker will last up to 26 years, allowing for decreased physician visits and surgeries. Though our device is intended for a one time purchase, repurchase will be an option for patients who enjoyed our device’s performance and would like to ensure the longevity of their pacemaker. In the future we hope to expand our technology to other cardiac implantable devices, making our device more marketable.
Video
Contact
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| Christopher Kim Co-Lead Biomedical Engineering chrik15@uci.edu |
Kylie Brown Co-Lead Biomedical Engineering kyliemb@uci.edu |
Loryn Chin Marketing Advisor Biomedical Engineering lorync@uci.edu |
Jacob Calendine Secretary Biomedical Engineering jcalendi@uci.edu |
References
1. Mond HG, Proclemer A. The 11th world survey of cardiac pacing and implantable cardioverter-defibrillators: calendar year 2009--a World Society of Arrhythmia's project. Pacing Clin Electrophysiol. 2011;34:1013–1027
2. Medtronic Micra™ AV MC1AVR1 Device Manual. January 2020.
3. Center for Devices and Radiological Health. (2021, November 17). Cardiac perforation complications with leadless pacemakers. U.S. Food and Drug Administration. Retrieved February 20, 2022, from https://www.fda.gov/medical-devices/letters-health-care-providers/leadless-pacing-systems-risk-major-complications-related-cardiac-perforation-during-implantation
4. Medtronic plc. (2022). Form 10-Q. U.S. Securities and Exchange Commission. http://pdf.secdatabase.com/2689/0001613103-22-000011.pdf
5. “Global leadless pacing system market: Industry analysis & forecast: Persistence market research (PMR),” Persistence Market Research. [Online]. Available: https://www.persistencemarketresearch.com/market-research/leadless-pacing-system-market.asp#:~:text=The%20estimated%20market%20for%20leadless,10.0%25%20during%20the%20forecast%20period. [Accessed: 01-May-2022].
6. “Leadless pacemakers market size, key players analysis, future trends, revenue and forecast 2028,” MarketWatch, 08-Apr-2022. [Online]. Available: https://www.marketwatch.com/press-release/leadless-pacemakers-market-size-key-players-analysis-future-trends-revenue-and-forecast-2028-2022-04-08#:~:text=Apr%2008%2C%202022%20(Heraldkeepers),can%20occur%20following%20cardiac%20surgery. [Accessed: 01-May-2022].
7. “Leadless Cardiac Pacemaker Market: 2022 - 27: Industry share, size, growth - mordor intelligence,” Leadless Cardiac Pacemaker Market | 2022 - 27 | Industry Share, Size, Growth - Mordor Intelligence. [Online]. Available: https://www.mordorintelligence.com/industry-reports/leadless-cardiac-pacemaker-market. [Accessed: 01-May-2022].